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Professor McGrath holds degrees in Mechanical Engineering from Arizona State (BS) and MIT (MS) and a PhD in Biological Engineering from Harvard/MIT's Division of Health Sciences and Technology. He trained as a Distinguished Post-doctoral Fellow in the Department of Biomedical Engineering at the Johns Hopkins University before joining the Biomedical Engineering faculty at the University of Rochester (UR) in 2001. His research group participates in highly interdisciplinary and multi-institutional teams that develop and apply ultrathin silicon-based, porous membrane technologies to a range of biomedical and environmental applications. He co-founded three companies to advance the commercial development and application of nanomembranes: SiMPore (2007), Parverio (2020), and SiObex (2024). In support of these application, Professor McGrath and his lab developed the µSiM microfluidic platform. Professor McGrath was awarded the Edmund A. Hajim Outstanding Faculty Award from the UR School of Engineering in 2019. He was awarded the University's highest teaching award (Goergen Award) in 2023 and named the William R. Kenan Jr. Professor of Biomedical Engineering in 2023. He is the founding director of the University of Rochester’s new Translational Center for Barrier Microphysiological Systems (TraCe-bMPS). He has 15 issued and pending patents and more than 115 scientific publications.