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Dr. Uygun brings a unique crossover between process systems engineering and surgery to the field of biopreservation. His PhD work focused on integration of process design and control, and identification of threat events for petrochemical process industries, with a specialization on model predictive control. In 2006 he joined MGH/HMS as a postdoc for training on liver surgery and transplantation. In 2008 he was awarded the NIH Pathway to independence award to fund development of metabolic models of the liver to recover unusable organs for transplantation. Since then, he has built this effort into a major program for reengineering organs, which aims to ensure all donor organs are utilized for public good. His laboratory features a vertically integrated transplantation program with small and large animal transplantation and human liver pseudo-transplantation, as well as mass spectrometry based metabolomics and systems biology expertise. He is particularly well known in supercooled organ preservation, a project he started at the cell level and successfully translated to rodent and then human donor liver models. Dr. Uygun’s lab is supported by the NIH, NSF, DoD as well as industry. He has published over 100 peer-reviewed works and 10 patent applications among other scholarly works.